Inhibit lactate dehydrogenase (LDH) LDH is the enzyme that converts glucose to lactate.
Vitamin B1 and methylene blue will do this for us.
Increase pyruvate dehydrogenase (PDH) PDH is the rate-limited enzyme that shuttles pyruvate (glucose breakdown product) into the mitochondria for oxidation.
Caffeine, fructose, palmitic acid and Vitamin B1 will increase the active enzyme.